Brinzolamide/brimonidine tartrate 10 mg/ml + 2 mg/ml eye drops, suspension

What Brinzolamide/brimonidine tartrate suspension is used for:

It is used to lower pressure in the eyes in adult patients (aged 18 years and over) who have eye conditions known as glaucoma or ocular hypertension and whose high pressure in the eyes cannot be controlled effectively by one medicine alone.

Do not use Brinzolamide/brimonidine tartrate suspension:

• if you are allergic to brinzolamide or brimonidine tartrate or any of the other ingredients of this medicine

• if you are allergic to sulphonamides (examples include medicines used to treat diabetes and infections and also diuretics (water tablets))

• if you are taking a monoamine oxidase (MAO) inhibitor (examples include medicines to treat depression or Parkinson’s disease) or certain antidepressants. You must inform your doctor if you are taking any antidepressant medicines

• if you have severe kidney problems

• if you have too much acidity in your blood (a condition called hyperchloremic acidosis)

• in babies and infants aged less than 2 years

Warnings and Precautions:

You should tell your doctor if you have any of the following:

• liver problems

• a type of high pressure in the eyes called narrow-angle glaucoma

• dry eyes or cornea problems

• coronary heart disease (symptoms can include chest pain or tightness, breathlessness or choking), heart failure, high or low blood pressure

• depression

• disturbed or poor blood circulation (such as Raynaud’s disease, Raynaud’s syndrome or cerebral insufficiency)

Possible side effects:

Like all medicines, Brimonidine tartrate can cause side effects, although not everybody gets them. Stop using the product and seek immediate medical attention if you develop throat tightness or swelling of the eyes, face, lips or tongue, feel faint, or have difficulty breathing. Stop using the product if you develop hives or itching of the face or body.

Other medicines and Brinzolamide/brimonidine tartrate suspension:

Tell your doctor or pharmacist if you are taking:

• medicines to lower blood pressure

• heart medicines including digoxin (used to treat heart conditions)

• other medicines for glaucoma that also treat altitude sickness known as acetazolamide, methazolamide and dorzolamide

• medicines that can affect the metabolism, such as chlorpromazine, methylphenidate and reserpine

• antiviral, antiretroviral (used to treat Human Immunodeficiency Virus (HIV)) or antibiotic medicines

• antiyeast or antifungal medicines

• monoamine oxidase (MAO) inhibitors, or antidepressants including amitriptyline, nortriptyline, clomipramine, mianserin, venlafaxine and duloxetine

• anaesthetics

• sedatives, opiates, or barbiturates

How to use Brinzolamide/brimonidine tartrate suspension:

Always use this medicine exactly as your doctor, optometrist (optician) or pharmacist has told you. Check with your doctor, optometrist (optician) or pharmacist if you are not sure.

Only use Brinzolamide/brimonidine tartrate for your eyes. Do not swallow or inject.

The recommended dose is one drop in the affected eye or eyes two times a day. Use at the same time each day.

How to store Brinzolamide/brimonidine tartrate suspension:

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the carton and label after ‘EXP’. The expiry date refers to the last day of that month.

Do not store above 25°C.

Discard within 28 days of opening.

Do not throw away any medicines via wastewater or household waste.

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