Jadenu 180 mg Film Coated 30 Tablets

Description

JADENU is an iron chelator indicated for the treatment of chronic iron overload due to blood transfusions in patients 2 years of age and older.

• • JADENU is indicated for the treatment of chronic iron overload in patients 10 years of age and older with non-transfusion-dependent thalassemia (NTDT) syndromes, and with a liver iron (Fe) concentration (LIC) of at least 5 mg Fe per gram of dry weight (Fe/g dw) and a serum ferritin greater than 300 mcg/L.

How to use:

• • Transfusional Iron Overload: Initial dose for patients with estimated glomerular filtration rate (eGFR) greater than 60 mL/min/1.73 m2 is 14 mg per kg (calculated to nearest whole tablet or nearest whole sachet content for granules) once daily.

• • NTDT Syndromes: Initial dose for patients with eGFR greater than 60 mL/min/1.73 m2 is 7 mg per kg (calculated to nearest whole tablet or nearest whole sachet content for granules) once daily.

Caution & Warnings:

• • Acute kidney injury, including acute renal failure requiring dialysis and renal

• • Tubular toxicity including Fanconi syndrome

• • Hepatic toxicity, including failure

• • Gastrointestinal hemorrhage

Side Effects:

• • Diarrhea, vomiting, nausea, abdominal pain, skin rashes, and increases in serum creatinine.

Ingredients:

• Deferasirox 180Mg.